{"id":10031,"date":"2026-03-27T15:44:53","date_gmt":"2026-03-27T14:44:53","guid":{"rendered":"https:\/\/science-nutrition.com\/?p=10031"},"modified":"2026-04-02T18:08:37","modified_gmt":"2026-04-02T17:08:37","slug":"efsa-positive-opinion-on-a-health-claim-related-to-oat-beta-glucans","status":"publish","type":"post","link":"https:\/\/science-nutrition.com\/en\/2026\/03\/27\/efsa-positive-opinion-on-a-health-claim-related-to-oat-beta-glucans\/","title":{"rendered":"EFSA positive opinion on a health claim related to oat beta-glucans"},"content":{"rendered":"
\n

On February 20, 2026, the EFSA published a positive opinion on the substantiation of a health claim related to oat beta-glucans and the reduction of postprandial glucose peak.<\/em><\/p>\n

 <\/p>\n

According to the Regulation (EC) 1924\/2006, health claims are prohibited unless they are authorized and are included in the lists of authorized health claims. To get the authorization of a health claim, the applicant must provide the demonstration of the requested beneficial health effect in humans. The EFSA evaluates to which extent the scientific substantiation shows the effect in humans. The EFSA issues an opinion. A positive opinion validates the evidence of the claimed effect but does not constitute an authorization of the health claim.<\/p>\n

Applicant<\/u><\/strong>:<\/h6>\n

ScanOats applied for authorisation of a health claim related to oat beta-glucans and the reduction in blood glucose rise after a meal. The requested health claim is a function claim supported by newly developed scientific evidence (Art 13.5). Following an additional data request by the EFSA, the applicant has clarified that the proposed health claim refers to the reduction of the postprandial glucose peak, for which the postprandial incremental peak glucose (iPkG) is the main endpoint for substantiation.<\/p>\n

The target population is individuals wishing to reduce their postprandial glucose peaks.<\/p>\n

Subject of the health claim<\/u><\/strong> :<\/h6>\n

oat beta-glucans (OBG) that are well defined and sufficiently characterized food constituents.<\/p>\n

Relevance of the claimed effect to human health: <\/u><\/strong><\/h6>\n

The proposed health claim concerns the reduction of postprandial blood glucose responses at a single time point, i.e. the time point at which the maximum blood glucose concentration relative to baseline is reached after the consumption of a food or meal rich in available carbohydrates as compared to a reference food or meal. The EFSA Panel considers that the reduction of the postprandial iPkG may be a beneficial physiological effect in particular in individuals with impaired glucose tolerance, as long as postprandial glucose and insulin responses are not increased as compared to the reference food or meal.<\/p>\n

In this context, the scientific evidence for substantiating health claims on the reduction of postprandial glucose peak can be obtained from human intervention studies measuring fasting and postprandial blood glucose and insulin at different time points during an appropriate period of time of at least 2 h and showing a decrease in the iPkG after consumption of the test food\/meal versus<\/em> a reference test food\/meal and no increase in postprandial blood glucose or insulin concentrations over that period.<\/p>\n

The EFSA Panel considers that the reduction of postprandial blood glucose peak is a beneficial physiological effect in the context of the food constituent and the target population proposed for this claim.<\/p>\n

Scientific substantiation of the requested health claim<\/u><\/strong><\/h6>\n

The applicant performed a systematic literature search dealing with the food constituent, the claimed effect and the study population. A total of 16 clinical intervention studies comprising 55 trial comparisons (strata) were considered relevant for substantiating the claim. All studies were randomised cross-over trials, with washout periods ranging from \u2265 1 day to \u2265 1 week, with four studies without mention of washout duration. Study populations generally included healthy adults of both sexes, with one study focusing on participants with metabolic syndrome and another study on females only. Sample size ranged from 10 to 40 individuals. A wide variety of food matrices were tested, such as cereal preparations, bread-type products, pasta, muffins and beverages. The OBG doses ranged from 0.96 to 6.48 g\/30 g available carbohydrates (avCHO) The amount of avCHO in the test and control meals ranged from 18 to 65 g, with most studies providing either approximately 30 g or around 50 g.<\/p>\n

All the studies but two reported a statistically significant decrease in the postprandial iPkG with the OBG-test meal as compared to the matched control meal in one or more trial comparisons. The differences in iPkG between the control and test meals were \u2265 20% in most studies and strata. The Panel considers that difference of about 20% in the iPkG is likely to be biologically relevant for healthy individuals in the context of a mixed diet. In some clinical studies, statistically significant differences between the control and test meals in iPkG were < 20% (i.e. between 10.7% and 19.8%). However, these studies had a sample size two to three times higher than the 10\u201315 subjects usually recruited for testing the glycaemic index of foods, which may have increased the precision of the estimates.<\/p>\n

Taken together, these studies showed an effect of OBG on the reduction of the postprandial iPkG and indicated that OBG dose, molecular weight (MW) and viscosity, carbohydrate load, food matrix, and processing can all have an impact on such effect.<\/p>\n

Dose-responses relationship and definition of the lowest effective dose<\/u><\/strong>:<\/h6>\n

The applicant provided a linear mixed-effects dose-response meta-analysis to explore the OBG dose effect on iPkG.<\/p>\n

In the applicant’s intercept-constrained model, a 20% reduction (RoM = 0.8) in the iPkG, which is likely to be biologically relevant for healthy individuals in the context of a mixed diet, corresponds to an OBG dose of approximately 2.7 g\/30 g avCHO (approximate range using the 95% CI for \u03b21: 2.3 to 3.4 g\/30 g avCHO). The Panel notes that this model is based on a wide body of evidence from human intervention studies using matched controls that cover an acceptable range of OBG MWs, food matrices and processing conditions. The Panel also notes that the lowest effective dose of OBG in some carbohydrate-containing foods (e.g. pasta products, glucose drinks) across MWs and testing conditions may be above 2.7 g\/30 g avCHO.<\/p>\n

Based on all the evidence and related uncertainties, the Panel considers that at least 3 g of OBG per 30 g avCHO would be required to achieve a consistent and biologically relevant reduction in postprandial blood glucose peaks following the consumption of avCHO-rich foods or meals.<\/p>\n

Mechanisms of action:<\/u><\/strong><\/h6>\n

The mechanism relates to the OBG ability to increase the viscosity of the meal bolus which may delay gastric emptying and, once the meal bolus reaches the small intestine, a high luminal viscosity delays the rate of digestion and absorption of nutrients, including glucose. By slowing the rate at which glucose appears in the circulation, this mechanism is expected to reduce overall postprandial glycaemic exposure and to attenuate the maximum postprandial blood glucose concentration (i.e. the postprandial glucose peak).<\/p>\n

Weighing of the evidence:<\/u><\/strong><\/h6>\n

In weighing the evidence, the EFSA Panel concludes that a cause-effect relationship has been established between the consumption of oat beta-glucans and the reduction of postprandial blood glucose peak.<\/p>\n

Claim wording: <\/u><\/strong><\/h6>\n

The Panel considers that the following wording reflects the scientific evidence: “Consumption of beta-glucans from oats contributes to the reduction of the glucose peak after a meal”.<\/em><\/p>\n

Conditions and restrictions of use: <\/u><\/strong><\/h6>\n

In order to bear the claim, foods\/meals should contain at least 30 g of available carbohydrates per portion and at least 3 g of beta-glucans from oats for each 30 g of available carbohydrates. The target population is individuals who wish to reduce their postprandial glucose peaks.<\/p>\n

 <\/p>\n

It is now up to the European Commission and the State Members to take the decision.<\/p>\n

 <\/p>\n

If you want to know more on this EFSA positive opinion related to oat beta-glucans and reduction of postprandial glucose peak, click here.<\/a><\/p>\n

 <\/p>\n

Orchidali can help you for preparing and submitting regulatory files for new health claims.<\/a><\/strong><\/em>\n<\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

On February 20, 2026, the EFSA published a positive opinion on the substantiation of a health claim related to oat beta-glucans and the reduction of postprandial glucose peak.<\/p>\n","protected":false},"author":4,"featured_media":2805,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31,27,297],"tags":[87,1820,1817,1309,1818,1821,1819,1096],"class_list":["post-10031","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allegations-sante-nutrition","category-recherche","category-reglementation-2","tag-allegations-de-sante","tag-beta-glucanes-davoine","tag-ec-regulation","tag-health-claim","tag-oat-beta-glucans","tag-reduction-du-pic-de-glucose-postprandial","tag-reduction-of-post-prandial-glucose-peak","tag-reglementation-europeenne"],"yoast_head":"\nEFSA positive opinion on a health claim related to oat beta-glucans - Orchidali - When feeding is health<\/title>\n<meta name=\"description\" content=\"Conseil scientifique et r\u00e9glementaire en alimentation\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/science-nutrition.com\/2026\/03\/27\/efsa-positive-opinion-on-a-health-claim-related-to-oat-beta-glucans\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"EFSA positive opinion on a health claim related to oat beta-glucans - 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